Protein-protein interaction site prediction based on conditional random fields
Minghui Li*, Lei Lin, Xiaolong Wang, and Tao Liu
Bioinformatics Research Group,
ITNLP Lab,
Department of Computer Science and Technology, Harbin Institute of Technology,
No. 92 West Da-Zhi Street, Harbin, 150001, China
Dataset:
1. non-redundant hetero-complex chains2. 1276 chains are divided randomly into three parts:
part1,
part1 and
part2
3. protein-protein interaction sites on hetero-complex chains
(a) sites calculated from the largest patch (download)
(b) sites calculated from the all partners (download)
(C) sites within minor interfaces (download)
4. File format
Color figures:
Fig. 4. 1W1W:E
(a) CRFs,
(c) SVMs and
(b) Actual interface residues.
Fig. 5. 1FJG:F
(a) CRFs,
(c) SVMs and
(b) Actual interface residues.
Fig. 6. 1KTK:A
(a) CRFs,
(c) SVMs and
(b) Actual interface residues.
